There have in recent months been increasing calls for better understanding of the pros and cons of Ozempic. Concerns over lack of support when people come off the drug and the weight gain that often accompanies withdrawal from the drug are central to the concerns raised in this BBC article.

As we delve into the conversation around diabetes management and weight control, one medication that has garnered considerable attention is Ozempic. Originally developed for type 2 diabetes, this glucagon-like peptide-1 (GLP-1) receptor agonist has shown promise in aiding weight loss, making it a hot topic in both medical and weight-loss communities. However, like any medication, it comes with its own set of benefits and drawbacks.

Pros of Ozempic

1. Effective Glycaemic Control: One of Ozempic’s primary advantages is its ability to regulate blood sugar levels. By mimicking the effects of incretin hormones, Ozempic enhances insulin secretion in response to meals, thereby reducing after-meal blood sugar spikes. For patients with type 2 diabetes, this can significantly improve overall glycaemic control.

2. Weight Loss Benefits: Clinical studies have highlighted Ozempic’s potential for weight loss. Many patients experience significant and sustained weight reduction, which is particularly beneficial for those struggling with obesity or overweight. Weight loss contributes to better diabetes management and can reduce the risk of complications.

3. Cardiovascular Benefits: Research indicates that Ozempic may also provide cardiovascular benefits, including reduced risk of major cardiovascular events in patients with type 2 diabetes. This is vital, considering the higher rates of heart disease associated with diabetes.

4. Convenient Dosing: Ozempic is administered through a once-weekly injection, making it more convenient than daily medications. This can improve adherence to treatment, as patients are less likely to forget a dosage.

Cons of Ozempic

1. Gastrointestinal Side Effects: Common side effects of Ozempic include nausea, vomiting, diarrhoea, and constipation. For some, these gastrointestinal issues can be significant enough to impact their quality of life or lead to discontinuation of the medication.

• Insufficient protein intake can impair muscle protein synthesis, the process by which the body builds and repairs muscle tissue. A change in body composition with weight loss coming from loss of muscle mass as well as fat can lead toother health concerns.

3. Long-term Safety Uncertainty: While Ozempic has shown a favourable safety profile in clinical trials, long-term data on its safety and efficacy is still emerging. Patients may be concerned about potential risks or side effects that could arise with prolonged use.

4. Cost: Ozempic can be expensive, and while insurance may cover part of the cost for diabetes management, it may not be as accessible for those seeking it for weight loss, potentially limiting its utility.

5. Not for Everyone: Ozempic is not suitable for everyone. Individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should avoid it due to a potential risk of thyroid tumours.

Conclusion

Ozempic represents a significant advancement in the management of type 2 diabetes and obesity, with clear benefits in glycaemic control and weight loss. However, patients must weigh these advantages against potential side effects and costs. Many suggest it should not be the first option considered for those wanting weight loss who do not have diabetes, nor should it be taken casually as a lifestyle drug. Reducing intake of processed food, starting regular moderate exercise and considering a structured weight loss dietary program e.g Forever Living Products (15% discount on checkout) are the tried and tested method for weight management. Because many people lose muscle mass while taking this drug, it’s important to consider increasing protein intake and starting resistance training to strengthen muscles. As always, it’s essential to discuss with a healthcare provider to tailor treatment plans that align with individual health needs and circumstances. For a deep dive into the metabolic action of Ozempic, Dr Mark Hyman is an excellent source of information.